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American Society of Microbiology ABMM Exam Syllabus Topics:

American Society of Microbiology ABMM Sample Questions:

1. A patient develops severe, watery diarrhea shortly after starting a course of clindamycin. Stool testing using a cytotoxicity assay is positive. This result is most consistent with infection by which organism?

A) Giardia lamblia
B) Norovirus
C) Clostridioides difficile
D) Campylobacter jejuni

2. A 6-year-old child presents with a pharyngitis characterized by a grayish-white pseudomembrane covering the tonsils and posterior pharynx. Gram stain of the membrane reveals Gram-positive bacilli. Culture on Loeffler's medium shows growth of metachromatic granules. The MOST significant virulence factor associated with this organism's pathogenicity is:

A) Diphtheria toxin
B) Hyaluronidase
C) Streptolysin O
D) Protein A

3. A clinical microbiology laboratory is investigating a potential outbreak of Legionella pneumophila associated with a hospital's water system. The MOST appropriate environmental samples to collect for culture and comparison to clinical isolates would be:

A) Surface swabs from frequently touched objects.
B) Air samples from patient rooms and common areas.
C) Sputum samples from asymptomatic healthcare workers.
D) Water samples from showers, faucets, and cooling towers.

4. A microbiology laboratory is performing antimicrobial susceptibility testing using the Kirby-Bauer disk diffusion method. A bacterial isolate shows no zone of inhibition around a specific antibiotic disk. This result could be due to:

A) The use of an incorrect inoculum density.
B) The antibiotic disk being stored improperly.
C) Intrinsic resistance of the organism to the antibiotic.
D) All of the above.

5. A patient with cystic fibrosis experiences a pulmonary exacerbation. Sputum culture grows a mucoid strain of Pseudomonas aeruginosa. The mucoid phenotype is primarily due to the overproduction of:

A) Pyocyanin
B) Elastase
C) Alginate
D) Exotoxin A

Solutions: